美国博士后招聘-西弗吉尼亚大学-肿瘤表观基因组

发布时间：2020/10/9 16:45:52

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如有招聘信息发布(博士/博后/访学)可联系

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公众号链接：https://mp.weixin.qq.com/s?__biz=MzU5NTk2OTE2Mw==&mid=2247485747&idx=1&sn=b5dffa3b8ddf9c7166f1123838e6a09d&chksm=fe689cd7c91f15c17a9cc231b513e7d3f4be7ada608353d0c17e496ef57baedcbf0f4d4fbdeb&token=1236109003&lang=zh_CN#rd

学校：西弗吉尼亚大学 West Virginia University

院系：Department of Microbiology, Immunology, and Cell Biology

教授：Dr Gangqing Hu

申请邮箱： |m|i|c|h|a|e|l|.|h|u|@|h|s|c|.|w|v|u|.|e|d|u|

截止日期：满额为止

介绍

西弗吉尼亚大学（WVU）微生物学，免疫学和细胞生物学系的胡博士实验室目前有两个博士后职位。该实验室通过对NGS多组学数据的综合分析，重点研究免疫细胞和癌细胞的表观遗传调控机制（参见Front Immunol 2019，PMID：31849962; Immunity 2018，PMID：29466755; Nat Methods 2018，PMID：30150754; Nat Immunology 2017，PMID：28759003; Nat Immunology 2013，PMID：24056746; Cell Stem Cell 2013，PMID：23260488; Cell 2012，PMID：23021216）。该实验室对骨髓微环境中血液系统癌症的耐药性的表观遗传机制特别感兴趣，重点是染色质调节剂和转录因子。请参照https://openwetware.org/wiki/Hu for more information获取更多信息。

要求

实验生物学家职位：

优秀的候选人必须在分子和细胞生物学，癌症生物学或其他相关背景领域拥有博士学位。

合格的候选人应具有较强的沟通能力，有上进心，注重细节，能够在协作环境中工作。

他/她应精通实验技能，包括细胞系培养，基于磁珠或FACS的细胞纯化，RT-qPCR，ChIP-qPCR，蛋白质印迹，细胞凋亡测定，增殖测定，shRNA敲除（稳定和可诱导），以及其他通用程序。

该职位还希望在构建NGS库（例如RNA-Seq和ChIP-Seq）方面有经验。具有基于NGS的染色质生物学领域的第一作者研究出版物是一项优势。

计算生物学家的职位：

优秀的候选人必须在应用数学，生物信息学，计算生物学或其他相关背景领域拥有博士学位。

候选人应该在序列分析和机器学习方面表现出强大的编程技能。

该实验室将提供足够的培训机会，以分析各种下一代测序数据，包括但不限于RNA-Seq，ChIP-Seq，ATAC-Seq，Hi-C，16S rna-seq，microRNA，exome-seq和整个基因组排序（WGS）。

该工作还期望候选人通过合作研究将50％的时间用于在整个大学范围内促进团队科学。

在序列分析领域拥有第一作者的论文是强项。

申请

符合条件的申请人可以向胡刚清博士（|m|i|c|h|a|e|l|.|h|u|@|h|s|c|.|w|v|u|.|e|d|u|）提交:

求职信

简历

三位推荐人的联系方式

Job description

Two Post-Doc positions are currently available in Dr. Hu’s lab at the Department of Microbiology, Immunology, and Cell Biology, West Virginia University (WVU). The lab focuses on mechanisms of epigenetic regulation of immune cells and cancer cells through integrative analysis of NGS multi-omics data (see Front Immunol 2019, PMID: 31849962 ; Immunity 2018, PMID:29466755; Nat Methods 2018, PMID: 30150754; Nat Immunology 2017, PMID: 28759003; Nat Immunology 2013, PMID: 24056746; Cell Stem Cell 2013, PMID: 23260488; Cell 2012, PMID: 23021216). We are particularly interested in epigenetic mechanisms of drug resistance of hematological cancers in the bone marrow microenvironment with a focus on chromatin regulators and transcription factors. Check https://openwetware.org/wiki/Hu for more information.

Experimental Biologist Position: Strong candidates must have a PhD in the area of molecular and cell biology, cancer biology, or other related backgrounds. The qualified candidate should have strong communication skills, be self-motivated, detail oriented, able to work in a collaborative setting. He/she should be proficient in experimental skills including cell line culture, cell purification based on magnetic beads or FACS, RT-qPCR, ChIP-qPCR, western blot, apoptosis assays, proliferation assays, shRNA knockdown (stable and inducible), and other common procedures. The position also expects experience on building NGS libraries such as RNA-Seq and ChIP-Seq. Having first-author research publications in the field of chromatin biology based on NGS is a strong plus.

Computational Biologist Position: Strong candidates must have a PhD in the area of applied mathematics, bioinformatics, computational biology, or other related backgrounds. The candidate should have demonstrated strong programming skills on sequence analysis and machine learning. The lab will offer ample training opportunities to analyze various next-generation sequencing data, including but not limited to RNA-Seq, ChIP-Seq, ATAC-Seq, Hi-C, 16S rna-seq, microRNA, exome-seq and whole genome sequencing (WGS). The job also expects that the candidate devote 50% of time to promote team science across the university through collaborative research. Having first-author paper(s) in the field of sequence analysis is a strong plus.

Founded in 1867, WVU is 1 of only 11 research intensive land-grant institutions offering a single health sciences campus with accredited Schools of Medicine, Dentistry, Nursing, and Pharmacy and a formative School of Public Health. The Carnegie Foundation for the Advancement of Teaching classifies WVU as a comprehensive doctoral institution with medical programs. Morgantown and its vicinity are ranked among the most livable small cities in the country. The city is located within reasonable driving distances from Pittsburgh, PA and Washington, DC.

The West Virginia University Research Corporation is an AA/EOE/Minorities/Females/Vet/Disability/E-verify compliant employer. 

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