发布时间:2020/10/29 10:27:19
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邮箱:cxw@med.tj.cn
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学校:叶史瓦大学 Yeshiva University
院系:Albert Einstein College of Medicine, Soldner laboratory
申请邮箱: frank.soldner@einsteinmed.org
截止日期:Nov. 27, 2020
介绍
纽约市阿尔伯特·爱因斯坦医学院Soldner实验室诚招积极主动,成功的和有创造力的人员,拥有神经科学,干细胞生物学,分子遗传学和生物信息学的研究背景。Soldner实验室的研究主要聚焦于利用细胞培养模拟人类大脑的发育和功能,用于系统地研究复杂的神经系统疾病的基因,细胞和分子基础,如帕金森病和阿尔茨海默氏病。我们采用跨学科方法,结合人类多功能干细胞(hPSC )衍生的神经元细胞功能基因组学方法,以及群体遗传学和基因组表观遗传信息学,从而对遗传控制和遗传系统下的神经退行性疾病进行研究。我们最近在单层和类器官神经元培养物中建立了一个新的CRISPR功能基因组学平台,以定量分析遗传,表观遗传学和环境因素如何促进神经系统疾病的发展和进展并确定新的治疗靶标。候选人将成为多学科小组的成员,该多学科小组是跨学科帕金森病科学联盟(ASAP)计划资助的,旨在了解遗传风险因素如何推进帕金森氏病的发展和进展(https:// parkinsonsroad m ap.org/research-network/biology-of-pd-相关遗传学/)。有关我们实验室和研究的更多详细信息,请访问http://www.einstein.yu.edu/faculty/16002/frank-soldner/。
要求
有上进心,热情和协作精神
博士和/或医学或神经科学,遗传学,干细胞生物学,生物信息学或任何相关领域的同等学历
参与过的项目中拥有优秀的一作文章记录
优秀的沟通和人际交往能力
有兴趣成为多学科团队的一员
非常需要以下任何相关领域的经验:干细胞生物学,特别是人胚胎干细胞(hESCs )和诱导性多能干细胞(hiPSCs ),神经元体外培养,分子和细胞生物学,分子遗传学和生物化学。
具有生物信息学方面的额外经验将是首选。
申请
请通过电子邮件(frank.soldner@einsteinmed.org)发送申请,包括您的简历和一封简短的求职信,并概述您的研究经验和兴趣,以及两位推荐人的联系信息。
高素质的候选人可能有资格申请该部门的Sheryl和Dan Tishman博士后奖学金(http://www.einstein.yu.edu/departments/neuroscience/tishman-fellowship.aspx)
Job description
The Soldner laboratory at the Albert Einstein College of Medicine in New York City is seeking highly motivated, successful, and creative individual(s) with a background in neuroscience, stem cell biology,molecular genetics or bioinformatics. The main focus of the Soldner laboratory is modeling human brain development and function in cell culture as a tool to systematically investigate the genetic, cellular, and molecular basis of complex neurological disorders such as Parkinson’s and Alzheimer’s disease. We employ an interdisciplinary approach, integrating functional genomics approaches in human pluripotent stem cell (hPSC) derived neuronal cells with population genetics and genome-scale epigenetic information to study neurodegenerative disorders in a genetically controlled and systematic manner. We have recently established a novel CRISPRfunctional genomics platform in monolayer and organoid neuronal cultures to quantitatively dissect how genetic, epigenetic, and environmental factors contribute to the development and progression of neurological diseases and to identify novel therapeutic targets. The candidates will work as part of a multidisciplinary group funded by the Aligning Science Across Parkinson’s (ASAP) Initiative aimed at understanding how genetic risk factors contribute to the development and progression of Parkinson’s disease (https://parkinsonsroadmap.org/research-network/biology-of-pd-associated-genetics/). For more details on our lab and research please visit http://www.einstein.yu.edu/faculty/16002/frank-soldner/.
The Albert Einstein College of Medicine (http://www.einstein.yu.edu/), recognized by Forbes as one of the nation’s top midsize employers,provides a highly interactive and stimulating academic environment for scientists in training. The prospective recruit will join our group which consists of postdoctoral fellows, graduate students and technologists. Lab members will participate in programs within the Departments of Neuroscience, Genetics, the Institute for Stem Cell and Regenerative Medicine and throughout the school to further their career development. These include weekly journal clubs, work-in-progress seminars, invited talks, workshops as well as social and professional events organized by the Einstein Postdoc office. We are located in a pleasant residential area in the northeast corner of New York City with an easy commute to Manhattan and the suburbs of Westchester County. We offer competitive salary and benefit packages with optional postdoctoral housing on campus.
Albert Einstein College of Medicine is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.
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